TOP SP9 SECRETS

Top sp9 Secrets

Top sp9 Secrets

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In their new study, the scientists produced a peptide—a brief chain of amino acids—referred to as SP9 to dam Syt2.

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"We designed up an image of what the secretory machinery seemed like and we understood the entire significant players," Dickey explained. "At the time we experienced an notion of how all of the pieces worked collectively, we identified synaptotagmin-two (Syt2) was the best protein to target to block mucin secretion as it only results in being activated with a large amount of stimulation.

In lab tests, SP9 shut down the membrane fusion approach by attaching to Syt2. The researchers next analyzed SP9 in human airway cells grown during the lab.

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